No, with the DPF there's not much that changing anything behind it will do but it's a lot cheaper then an exhaust if you're not interested in a 5" pipe and cheaper then a muffler shop will charde for the pipe and hangers.

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2007.5 Dodge Ram 3500 HD,QC, 6.7L Cummins, 6speed Auto, 4X4, Bighorn Edition.
Click for installs: Carr Steps PML Diff Cover Edge Juice with Attitude Volant Intake Hankook ATM RF10